• It's official: Oprah says she plans to call it quits in September 2011. [ABC]
• Layoffs: The BusinessWeek cuts continue (and include a handful of the mag's more notable names); meanwhile the AP body count now stands at 90.
• Sarah Palin sold 300,000 copies of her book the first day, alas. [TDB]
• Condé Nast and Adobe are teaming up to bring Wired to electronic reading devices. Digital versions of Vogue, VF, and the NYer will follow. [WSJ]
• Vogue's design director is exiting the magazine after a four-year run. [WWD]
• In other Anna news, her de facto stepdaughter, Alexis Bryan Morgan, is leaving the Condé Nast family to take Nina Garcia's old job at Elle. [NYM]
• Cable mogul John Malone isn't happy about the idea of Comcast and NBC teaming up. Meanwhile NBC chief Jeff Zucker is staying mum about the deal.
• Another rumored Playboy bidder is denying interest in an acquisition. [NYT]
• Does Bonnie Fuller's new website stand a chance? [NYP]

It's been a tough year for Annie Leibovitz, but maybe she can start fresh from here on out? The financially challenged photographer turns 60 today. Others celebrating: designer Donna Karan is turning 61. Kelly Ripa turns 39. Lorraine Bracco is 55. Sting is 58. Actress Camilla Belle is turning 23. '80s pop star Tiffany is 37. And two of Hugh Hefner's latest girlfriends, Karissa and Kristina Shannon, are turning 20. A roundup of a few people celebrating birthdays this weekend—including Al Sharpton and Liev Schreiber—is below.

Jay McInerney's latest book, How It Ended, was feted at the 21 Club on Wednesday night. On hand for the occasion: McInerney's wife, Anne Hearst, Brooke Shields, Candace Bushnell and Charles Askegaard, Gay and Nan Talese, Morgan Entrekin, Nina Garcia, Pamela Fiori, Bob Colacello, Richard Johnson and Sessa Von Richthofen, Peggy Siegal, Muffie Potter Aston, Bettina Zilkha, Cornelia Guest, Debbie Bancroft, Valesca Guerrand-Hermes, Nina Griscom, Somers White Farkas, Patrick McMullan, Robert Couturier, George Farias, Tatiana and Campion Platt, Kimberly Rockefeller, Pamela Gross, Harry Slatkin, Dana Hammond, Harry Benson, and Deborah Norville. [PMc, VF, P6]

Cartier celebrated its 100th anniversary in New York last night with a big bash inside its Fifth Avenue store. The celeb-heavy crowd included Elton John, Kate Hudson, Jessica Biel and Justin Timberlake, Anne Hathaway, Rachel Weisz, Demi Moore, Eva Mendez, Ashley Olsen, Zac Posen, Martha Stewart, Graydon Carter, Jeff Zucker, Robbie Myers, Patti Smith, Russell Simmons and Julie Henderson, Tory Burch, Thakoon Panichgul, Erin Fetherston, Nanette Lepore, Phillip Lim, Coco Rocha, Hilary Rhoda, Daniel Boulud, Eli Weisel, Bruce Weber, Henrik Lundqvist, Ingrid Sischy, Beth Rudin DeWoody, Cornelia Guest, Susan Fales-Hill, Marjorie Gubelmann, Thora Birch, Chiara Clemente, Alexis Bryan, Dylan Lauren, Kelly Klein, and Cartier chief Frederic De Narp. [PMc, Wireimage, WWD]

The New Yorkers for Children benefit attracted a predictably star-studded crowd to the Mandarin Oriental on Wednesday night. In addition to Zac Posen and Coco Rocha in matching ensembles, guests included Josh Hartnett, Emmy Rossum, Andre Balazs, Christine and Steve Schwarzman, Rachel Roy, Rachel Zoe, Topper and Tinsley Mortimer, Lucy Sykes Rellie and husband Euan Rellie, Andres and Lauren Santo Domingo, Alexis Bryan, Fabiola Beracasa, Gillian Hearst Simonds, Diane Kruger and Joshua Jackson, Gillian and Sylvester Miniter, Olivia Palermo ...

It was Drew Barrymore's big night at the Ziegfeld yesterday when the new HBO movie, Grey Gardens, had its premiere. On hand for the occasion and afterparty at the Pierre: Drew's co-stars Jessica Lange and Jeanne Tripplehorn, as well as guests like Justin Long (left), Jimmy Fallon, Rudy and Judi Giuliani, Stanley Tucci, Steve Buscemi, Gay Talese, Arthur Sulzberger, Dan Abrams, Roger Friedman, Hilary Rhoda, Marc Jacobs and Lorenzo Martone, Peter Som, Jason Wu, Erin Fetherston, Kristin Wiig, Tony Sirico, Robert F. Kennedy Jr., Aerin Lauder, Albert Maysles, Ashleigh Banfield and Howard Gould, Monet Mazur, Debbie Harry, Selita Eubanks, the Beastie Boys' Mike D, Ad-Roc, and MCA, Aleksandra Baryshnikov, BD Wong, and the film's director, Michael Sucsy. [PMc, Wireimage, Getty, LAT, FWD]

Yves Saint Laurent sponsored the Metropolitan Opera's 125th Anniversary Gala at Lincoln Center on Sunday night. YSL creative director Stefano Pilati was on hand to welcome the likes of Brooke Shields (left), Claire Danes, Claudia Schiffer, Kanye West and Amber Rose, Parker Posey, Kim Heirston, Mia and Patrick Demarchelier, Diane Kruger and Joshua Jackson, Richard Meier, Jeremy Irons, Willem Dafoe, Ingrid Sischy, Emily Mortimer and Alessandro Nivola, Sally Singer, Woody Allen, Stefano Tonchi, James Levine, Renée Fleming, Peter Martins, Julianna Margulies and Keith Lieberthal, Zoe Saldana, Daphne Guinness, Julie Macklowe, Plácido and Marta Domingo, Ginnifer Goodwin, Becki Newton, Patricia Clarkson, Austin Scarlett, and Met mega-donor Mercedes Bass. [PMc, Wireimage, Style.com, VF, FWD]

A recap of the last few days in benefits and parties—including the Frick Collection's Young Fellows Ball, above—is after the jump.

Andrew Saffir's Cinema Society hosted a screening of He's Just Not That Into You at the Tribeca Grand on Wednesday night. Guests at the screening and after-party, hosted by Stardoll and Philosophy di Alberta Ferretti, included Lindsay Price (left), Olivia Palermo and Johannes Huebl, Michael Kors, Amy Sacco, Anne Hearst and Jay McInerney, Rachel Roy, America Ferrera, Helena Christensen, Eva Amurri, Mamie Gummer, Cuba Gooding Jr., Maggie Rizer, Annelise Peterson, Zoe Kravitz, Lisa Bonet, Lorenzo Martone, Marina Rust Connor, Chris Benz, Christian Siriano, Reed Krakoff, Dori Cooperman, Taylor Momsen, Carson Kressley, Poppy Delevigne, Jane Seymour, Genevieve Jones, Patricia Clarkson, Shoshanna Lonstein Gruss, Irina Pantaeva, Dylan Lauren, Jeff Gordon, Kiera Chaplin, Liam McMullan, Derek Blasberg, and one of the stars of the film, Ginnifer Goodwin. [PMc, Wireimage, VF, Style.com, NYO, FWD]

Hope you didn't try and cheat on your taxes last year or pull some sort of shady maneuver that you were hoping no one would notice. With the state now facing an unprecedented budget shortfall, tax authorities are now pushing people who haven't paid their outstanding tax bills to pay up in a hurry. Ralph Lauren had to hand over $4.18 million in back taxes recently, a debt related to taxes on his Gulfstream jet (photo here), although the fashion mogul says he plans to fight the ruling. Secretive billionaire Ira Rennert has been battling the state over a tax bill imposed on his holding company, the Renco Group, although he's since settled the case by coughing up $1.77 million. And Shelby Bryan, Anna Wintour's boyfriend (and the father of Alexis Bryan), also had to write a hefty check to New York State recently. In August, he handed over $976,222, although the IRS also hit him with a $1.6 million lien for outstanding federal taxes. Looks like Anna may not be able to retire so soon after all!

This should come in handy if you've been trying to understand how Alexis Bryan, George Gurley, Bee Shaffer and Sam Shaffer are all connected to Anna Wintour: Page Six magazine has assembled the Vogue editor's family tree. [Page Six]

Lyor Cohen and Al Sharpton are both celebrating today: The Warner Music chief (and boyfriend of Tory Burch) turns 49; the rabble-rousing clergyman is 54. Others marking the special occasion: socialite Alexis Bryan is 32. Clive Owen is 44. Jake Shears is 30. Gwen Stefani is 39. Ashlee Simpson is 24. Composer Steve Reich is 72. Tommy Lee is 46. Neve Campbell is 35. Actor Sean William Scott is 32. And the notoriously precise Times TV critic Alessandra Stanley is 53. Weekend birthdays after the jump.

» Zac Posen showed the kind of pretty dresses that made him famous. What has also made him famous, of course, is his dazzling knack for networking, which was in full effect with a starry audience of Claire Danes and Hugh Dancy, Marisa Tomei, Leighton Meester, Venus and Serena Williams, Anna Wintour, André Leon Talley, Bernadette Peters, Diddy, Julian Schnabel, Bette Midler, Juliette Lewis, Kate Mara, Jada Pinkett Smith, Veronica Webb, Joy Bryant, Rachel Zoe, Ingrid Sischy, and Fern Mallis. [WSJ, Wireimage]

• The inimitable Fug Girls were at Yigal Azrouël today and saw Elettra Rossellini Wiedemann (not sweating in leather pants, enthusiastically posing for a photographer), Miss J Alexander and Nigel Barker (chatting front row), Cory Kennedy (bored, disheveled), Alexis Bryan Morgan (still pregnant), Fabiola Beracasa (front row next to Katie Lee Joel), Nina Garcia (talking to reporters), and Kelly Cutrone (looking better in person than on TV). [The Cut]

1) Lisa Salzer had a party last night for her jewelry line Lulu Frost, where hosts Alexis Bryan Morgan and Elettra Rossellini Wiedemann were joined by Erin Fetherston and Hedi Ferjani, Derek Blasberg, Luigi Tadini, Kathryn Neale Shaffer, Peter Davis, Kate Schelter, and Carole Radziwill, who were rewarded for walking up the five flights of stairs with a live Cuban band and cocktails. [Paper/style file]

(1) Attendees at Sephora's party at the Angel Orensanz foundation last night included Lydia Hearst, Kelly Osbourne, Kat Von D, Nicky Hilton, Dani Stahl, Ali Wise, Jason Preston, Mike Satsky, Olivia Palermo, and Shoshanna Lonstein Gruss. The crowd, though, was more impressed by the presence of out-and-proud couple Lindsay Lohan and Samantha Ronson (above, with half-sister Annabelle) than by performances by Ashanti and Natasha Bedingfield. [Elle/PMc]

It's hard to believe Alexis Bryan is just now entering her third trimester. The wife of the Observer's Spencer Morgan, daughter of ex-telecom mogul Shelby Bryan, sort-of stepdaughter of Anna Wintour, employee of Graydon Carter, and soon-to-be mom of someone who will, no doubt, be one of Manhattan's most well-dressed tots, has been expanding before our eyes (and the cameras) for the past few months. Below, a look back at Alexis's growing bump, which we're sure she'll want to print out and include in her baby book.

A former middling star on the social scene, Bryan is the executive fashion director at Lucky magazine.

Today's Page Six stumbles when it should have scooped: "Sightings: Maxim Deputy Editor Chris Wilson howling out a Monkees song with N.Y. Observer writer George Gurley, followed by fellow Observer scribe Spencer Morgan and his girlfriend, Vanity Fair fashion editrix Alexis Stewart, belting out Heart's "Magic Man" at Sing Sing." So close! Alexis Stewart is Martha Stewart's crazy daughter. Spencer Morgan is dating Alexis Bryan. Shelby Bryan's daughter. You know, Vogue editor Anna Wintour's lover Shelby Bryan? Crazy, right? (Sort of better than Spencer's boss Jared Kushner dating Ivanka Trump even.) Please God, let them have children together and make Anna Wintour a grandmother at the same time as Colonel Potter becomes a great-grandfather!