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♦ Soon-to-be-single Madonna premiered her directorial debut, Filth and Wisdom, at the Sunshine Theater on Monday night. On the red carpet and/or the after-party at the Thompson LES: Lindsay Lohan (left), Jerry Seinfeld, Naomi Watts and Liev Schreiber, Ann Dexter-Jones, David Blaine, Alan Cumming, America Ferrera, Brooke Shields, Marc Jacobs and Lorenzo Martone, Glenda Bailey, Jessica Alba and Cash Warren, Juliette Lewis, Jason Biggs, Jeremy Piven, Vanessa Williams, Becki Newton, Malin Akerman, Lake Bell, Max Minghella, Padma Lakshmi, Terry Richardson, Diane Kruger and Joshua Jackson, Joe Zee, Byrdie Bell, Fabiola Beracasa, Ferebee Bishop Taube, Zani Gugelmann, Katie Lee Joel, Beth Ostrosky, Eleanor Ylvisaker, Kelly Klein, Minnie Mortimer, Maggie Rizer, Chace Crawford, Amanda Cutter Brooks, Ingrid Sischy, Ross Bleckner, Nancy Jarecki, Derek Blasberg, Ed Westwick, Rose Byrne, Taylor Momsen, Debbie Bancroft, Terry Richardson, Bruce Weber, Guy Oseary, and Ali Wise and Jason Pomeranc. [The Daily, PMc, Wireimage, Style.com]

♦ At Top of the Rock on Tuesday night, the Saks Fifth Avenue-sponsored Key For a Cure bash was hosted by Blythe Danner, Lindsay Price, and Jane Krakowski, and attended by Katie Lee Joel, Charlotte Ronson, Lindsay Lohan and Samantha Ronson (who DJed), Rachel Roy, Christian Siriano, Deborah Messing, Fabiola Beracasa, Lisa Airan, Lizzie, Jamie and Jonathan Tisch, Alison Brod, Kelly Killoren Bensimon, Stephanie Seymour, Gossip Girl's Kelly Rutherford, Bethenny Frankel, LuAnn de Lessups, Zani Gugelmann, Dori Cooperman, Andrew Saffir and Daniel Benedict, Ugly Betty's Becki Newton, Mary Alice Stephenson, Alex Kramer, Michael Fink, Peter Som, Shoshanna Lonstein Gruss, and Star Jones. [NYO, PMc]

Kim Hastreiter's new book Geoffrey Beene: An American Fashion Rebel was celebrated at a Monday night party hosted by Diane von Furstenberg on the second floor of her meatpacking district HQ: Adi, Ange & Gabi of Three as Four, Yigal Azrouel, Doo-Ri Chung, Erin Fetherston, Gilles Mendel, Bill Cunningham, Agnes Gund, Narciso Rodriguez, Fabiola Beracasa and Jason Beckman, Erin Fetherston, Douglas Hannant, Peter Davis, Timothy Greenfield-Sanders, Ben Widdecombe, Kate Schelter, David Hershkovits, Joey Arias, Mickey Boardman, Stephen Gaghan and Minnie Mortimer, Gilles Mendel, and Isabel and Ruben Toledo mingled and drank champagne. [The Daily, Paper, PMc]

♦ The following night Diane von Furstenberg had a party for herself at her studio, to launch her Wonder Woman-themed collection and comic book: Becki Newton, Rachel Roy, Deborah Messing, Whitney Port, Lindsay Price, Hamish Bowles, Reed Krakoff, Michael Roberts, and Georgina Chapman were all on hand to congratulate her. [The Daily]

♦ Charlie Kaufman's directorial debut, Synecdoche New York, was screened by the Cinema Society on Wednesday, followed by a party at the Gramercy Park Hotel. The film's stars Philip Seymour Hoffman, Catherine Keener, and Michelle Williams were joined by Andrew Saffir and Daniel Benedict, Julian Schnabel, Zoe Kravitz, Jack McCollough, Lazaro Hernandez, Michael Stipe, Jon Voight, Jason Lewis, Cynthia Rowley, Juliette Lewis, Bettina Zilkha, Kelly Klein, Adam Yauch, Ludacris, Jackie Astier, Olivier Zahm, Rachel Dratch, Spike Jonze, Stephen Rea, Peter Davis, Rain Phoenix, and Minnie Mortimer. [The Daily, PMc]